Portland Trail Blazers vs New Orleans Pelicans Prediction - 11/12/2025
Updated July 30, 2026
The Portland Trail Blazers (5‑5) head into Wednesday’s contest against the New Orleans Pelicans (2‑8) with an opportunity to get above the .500 mark. The Blazers have struggled of late while dealing with several key absences. But they will try to exploit the weaknesses of a Pelicans squad beset by injuries and struggling to find consistency. You can find my breakdown of this contest below, including my Trail Blazers vs Pelicans prediction before tip-off.
Pick: Pelicans +8.5
Confidence: ★★★★☆
Injuries will be a factor for both teams in this game, but their impact is bigger for New Orleans. The Pelicans will be missing several starters with Zion Williamson (hamstring), Dejounte Murray (leg), and Jordan Poole (knee) all out. Portland is without Scoot Henderson (hamstring), Matisse Thybulle (thumb), Blake Wesley (foot), and Damian Lillard (Achilles).
Portland is scoring 120.6 points per game (8th in the league) while allowing 119.3 points per game (22nd). They rank 19th in rebounds and struggle defensively, but they are generating more offense than most of their opponents. New Orleans is averaging just 108.0 points per game and surrendering 121.3 points per game, registering a ‑13.3 scoring differential.
The Pelicans are searching for rhythm and consistency without the two players they were expecting to carry the scoring load for them. Granted, expecting Zion Williamson to be on the floor might be foolish given how his pro career has gone so far. In any case, this is a golden chance for Portland to stop the bleeding against a Pelicans team that has clearly seen better days.
Player | Prop |
|---|---|
Jrue Holiday (POR) | Over 7.5 assists |
Deni Avdija (POR) | Under 24.5 points |
Trey Murphy III (NOP) | Over 21.5 points |
Score Projection: Portland 122 – New Orleans 117
Win Probability: Portland 73%, New Orleans 27%
The Trail Blazers should get a win in this game to improve to 6-5 on the season. But I think that the Pelicans will cover the spread as an underdog at home. New Orleans hasn't been terrible against the spread this season despite all of their roster limitations. I expect them to hang around in this game against an inconsistent Portland team.
Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.
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